Key result
Elevated CSF protein was an independent risk factor for death in children with influenza-associated encephalopathy (OR 4.385).
Why the study?
Seasonal influenza-associated neurological complications have high mortality and morbidity rates in children, prompting investigation into clinical characteristics and mortality risk factors.
Observational (n=68)
No
Odds Ratio: 4.385 (95% CI 1.432–13.425)
p-value: p=0.01
In children with influenza-associated encephalopathy, mortality is high (20.6%) and is strongly predicted by significant elevations in ALT, AST, LDH, and CSF proteins.
May inform prognosis in influenza-associated encephalopathy; leaves open whether CSF protein measurement alters outcomes.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Song et al. (2021) conducted an observational in Influenza-associated encephalopathy/encephalitis (n=68). Elevated CSF protein vs. Lower CSF protein levels was evaluated on Mortality (OR 4.385, 95% CI 1.432-13.425, p=0.01). Elevated CSF protein was an independent risk factor for death in children with influenza-associated encephalopathy (OR 4.385).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: