Key result
The evolution of left ventricular twisting models in postnatal ontogenesis is hypothesized to provide optimal growth and development of the heart in healthy children and adolescents.
Why the study?
Data on LV mechanics in postnatal ontogenesis are fundamental to understanding variants of LV contractile-rotational development, identifying early subclinical dysfunction, and monitoring therapy in healthy full-term children and adolescents.
Proposes a hypothesis that left ventricular twisting mechanisms evolve and transform during childhood and adolescence, which may help identify subclinical dysfunction early.
Highlights. The hypothesis of the evolution of LV twisting types is proposed, which is based on the gradual transformation of LV twisting types as a prerequisite for postnatal growth and development of heart chambers in healthy children and adolescents. In the future, the transition of one type of LV twist to another will enable us to diagnose the predominance of growth and maturation of the fibrous skeleton, apex, vortex cordis, trabecular apparatus, as well as creating projections of the individual development and growth of the heart in childhood and adolescence. Abstract. Modern data on the nature of the mechanics of the left ventricle (LV) in postnatal ontogenesis in healthy children and adolescents born full-term are fundamental, since they allow not only to determine ontogenetically conditioned variants of individual development of contractile-rotational mechanisms of LV in the process of growth and development, but also, if necessary, make it possible to identify subclinical dysfunction in the early stages, monitor the effectiveness of complex therapeutic and rehabilitation measures. The article analyzes newly established fact of the absence of static character of the selected various forms of LV twisting into a systole and the ability of their transformation in the process of growth and development. This fact forms the basis of the author's original hypothesis of “the evolution of LV twisting models”, which provides the optimal ontogenetic growth of the child and adolescent heart in the postnatal period. The hypothesis of “evolution of left ventricular twisting types” is based on modern knowledge about multifaceted processes at the tissue level, the mechanics of LV in the individual rate of development and growth of the heart in childhood and adolescence.
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Pavlyukova et al. (2023) conducted a review in Healthy children and adolescents. Left ventricular twisting mechanisms was evaluated. The evolution of left ventricular twisting models in postnatal ontogenesis is hypothesized to provide optimal growth and development of the heart in healthy children and adolescents.
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