Key result
Cortisone therapy for acute rheumatic myocarditis inhibited the inflammatory reaction but did not demonstrably alter the underlying collagen injury.
Why the study?
Does cortisone therapy alter the cardiac lesions in acute rheumatic myocarditis?
Does cortisone therapy alter the cardiac lesions in acute rheumatic myocarditis?
Cortisone therapy in acute rheumatic myocarditis appears to inhibit inflammation but does not alter collagen injury.
Answers are grounded in this paper and cite their sources.
Cortisone may suppress inflammation without modifying collagen injury in acute rheumatic myocarditis; hypothesis-generating and should not yet change practice.
The changes in the cardiac lesions of a patient dying with acute rheumatic heart disease treated with cortisone are reported. The findings indicate that the effect of this hormone upon the lesions consists in an inhibition of the inflammatory reaction without demonstrable alteration of the collagen injury.
No takes yet. Share an insight, caveat, or question.
Golden et al. (1953) studied this question. Cortisone therapy for acute rheumatic myocarditis inhibited the inflammatory reaction but did not demonstrably alter the underlying collagen injury.
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