When spores of Bacillus subtilis strain Marburg are heated (90 degrees to 100 degrees C) in a vacuum for 9 to 12 hours and then plated, numerous mutants are obtained, and very few spores are killed. Disproportionately large numbers of these mutants exhibit abnormal sporulation.
No takes yet. Share an insight, caveat, or question.
Northrop et al. (1967) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: