Key result
Treadmill stress testing at two weeks post-uncomplicated myocardial infarction identified multiple-vessel disease with 95% sensitivity and 94% specificity.
Why the study?
Does early maximal treadmill stress testing accurately identify additional severe coronary artery disease compared to coronary angiography in patients with uncomplicated myocardial infarction?
Cohort (n=61)
Does early maximal treadmill stress testing accurately identify additional severe coronary artery disease compared to coronary angiography in patients with uncomplicated myocardial infarction?
Effect estimate: Sensitivity 95%, Specificity 94%
Early maximal treadmill testing 2-3 weeks after an uncomplicated myocardial infarction is a safe and highly accurate non-invasive method for predicting the presence of additional severe coronary artery disease.
May support early treadmill testing to detect multivessel disease post-uncomplicated MI; leaves open need for randomized outcome trials.
In a prospective study 61 patients aged 55 years or less with uncomplicated myocardial infarction underwent treadmill stress testing at two weeks and coronary angiography at six weeks after infarction. Of the 44 patients who had a positive stress test, 43 had additional severe coronary artery disease confirmed by coronary angiography. Of the 17 patients who had a negative stress test for additional disease, coronary angiography identified only single-vessel disease in the infarct area in 15. The sensitivity of the stress test was 95% and the specificity 94%, though the number of patients in the study was small. Thus, exercise testing has considerable potential for the early identification of multiple-vessel disease in patients with uncomplicated myocardial infarction.
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Akhras et al. (1982) conducted a cohort in Uncomplicated myocardial infarction (n=61). Treadmill stress testing vs. Coronary angiography was evaluated on Identification of additional severe coronary artery disease (multiple-vessel disease) (Sensitivity 95%, Specificity 94%). Treadmill stress testing at two weeks post-uncomplicated myocardial infarction identified multiple-vessel disease with 95% sensitivity and 94% specificity.
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