Key result
The Pediatric Index of Mortality 2 (PIM2) score demonstrated satisfactory discrimination between survivors and non-survivors among pediatric intensive care patients (AUC 0.796; 95% CI 0.675-0.916; P<0.001).
Why the study?
Does the Pediatric Index of Mortality 2 (PIM2) accurately predict mortality in Egyptian pediatric intensive care patients?
Cohort (n=317)
No
Does the Pediatric Index of Mortality 2 (PIM2) accurately predict mortality in Egyptian pediatric intensive care patients?
The PIM2 scoring system demonstrates satisfactory calibration and discriminative ability for predicting mortality in Egyptian pediatric intensive care patients.
Supports PIM2 for mortality prediction in Egyptian PICUs; extends validation to this population but leaves open prospective confirmation.
Mortality prediction models are useful in pediatric intensive care units (PICUs) as risk assessment tools and as a benchmark for the quality of care. To assess the performance of the Pediatric Index of Mortality 2 (PIM2) in terms of calibration and discrimination between survivors and non-survivors among pediatric patients. This is a cohort prospective study including 317 pediatric patients admitted to two PICU settings in a tertiary care hospital in Egypt over a period of one year (from June 2012 till June 2013). Collected data included personal characteristics, hospital data, diagnosis, outcome and variables included in PIM2 scoring. Non-survivors constituted 8.5%. Most common diagnosis was respiratory diseases (47.9%). Only CNS morbidities (11.7% of survivors versus 37% of non-survivors, P = 0.001) and a higher PIM2 score (2.39 ± 5.49 in survivors versus 41.38 ± 36.06 in non-survivors, P = 0.001) were associated with increased risk of non-survival. The area under the curve (AUC) for PIM2 is 0.796 (95% CI 0.675–0.916), P < 0.001. The Hosmer–Lemeshow goodness-of-fit was 2.850, 8 df, P = 0.943. PIM2. The calibration and the discriminative ability of PIM2 scoring system aiming to distinguish survivors from non-survivors are satisfactory for this sample of pediatric patients. PIM2 is easily calculated and is freely available. Thus, this tool provides a good incentive for ICU settings in Egypt for admission of high risk patients in the light of the limited PICU bed complement capacity in relation to the demands.
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Youssef et al. (2014) conducted a cohort in Pediatric intensive care admission (n=317). Pediatric Index of Mortality 2 (PIM2) was evaluated on Discrimination between survivors and non-survivors (AUC 0.796, 95% CI 0.675-0.916, p=<0.001). The Pediatric Index of Mortality 2 (PIM2) score demonstrated satisfactory discrimination between survivors and non-survivors among pediatric intensive care patients (AUC 0.796; 95% CI 0.675-0.916; P<0.001).
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