Key result
Rectal indomethacin 100 mg eight hourly and cryoanalgesia significantly reduced pain scores compared to conventional opiate analgesia after thoracotomy, with an additive effect when combined.
Why the study?
Does rectal indomethacin, cryoanalgesia, or their combination reduce early postthoracotomy pain compared to conventional opiate analgesia in patients undergoing thoracic surgery?
Population
60 patients, mean age 61 years, undergoing pulmonary resections, oesophageal procedures, and thoracotomies…
Comparison
Rectal indomethacin 100 mg eight hourly… vs Conventional intramuscular opiate analgesia. All…
Design
RCT, allocated randomly to one of four groups of 15, randomised double blind…
Follow-up
first two days
Authors
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Offers opioid-sparing options after thoracotomy; extends RCT evidence for multimodal non-opioid strategies in thoracic surgery.
RCT
Double-blind
Randomized
Does rectal indomethacin, cryoanalgesia, or their combination reduce early postthoracotomy pain compared to conventional opiate analgesia in patients undergoing thoracic surgery?
Rectal indomethacin and cryoanalgesia, alone or in combination, safely and effectively reduce early postthoracotomy pain and opiate requirements compared to conventional intramuscular opiates.
Keenan et al. (1983) conducted an RCT in Early postthoracotomy pain. Rectal indomethacin and/or cryoanalgesia vs. Conventional intramuscular opiate analgesia was evaluated on Pain scores. Rectal indomethacin 100 mg eight hourly and cryoanalgesia significantly reduced pain scores compared to conventional opiate analgesia after thoracotomy, with an additive effect when combined.
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