Preserving a globular protein shape on glass slides: A self‐assembled monolayer approach

The manufacture of low‐cost, protein‐friendly, biocompatible materials is important for biomedical applications. A method is presented for making glass surfaces—on which the globular protein shape is often lost –benign to proteins by covalently grafting relatively short poly((ethylene glycol)) chains (functionalized with trimethylsilane, see Figure), which form a brush‐like self‐assembled monolayer. magnified image