Key result
Radical surgical resection followed by adjuvant chemotherapy with ifosfamide and epirubicin resulted in 9-month survival without recurrence in a patient with a rare intimal aortic sarcoma.
Case Report (n=1)
No
Radical excision followed by adjuvant chemotherapy with ifosfamide and epirubicin resulted in 9-month recurrence-free survival in a patient with intimal aortic sarcoma mimicking a ruptured aneurysm.
Supports multimodality therapy for intimal aortic sarcoma; hypothesis-generating and should not yet change practice.
Primary intimal aortic sarcoma represents a very rare and highly lethal medical entity. Diagnosis is made either by embolic events caused by the tumor or by surrounding tissue symptoms such as pain. Herein we report an extremely rare case of a 51-year-old man previously operated for ascending aortic aneurysm, who presented with clinical and radiological findings suggestive of a ruptured thoracoabdominal type IV aneurysm. The patient underwent radical resection of the aorta and surrounding tissue with placement of a composite 4-branched graft. The diagnosis was made by frozen section and regular histopathologic examination of the specimen and the patient received adjuvant chemotherapy. Nine months after surgery the patient is still alive and has no signs of recurrence. We review the literature and discuss the option of postoperative chemotherapy.
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Dedeilias et al. (2011) conducted a case report in Intimal aortic sarcoma (n=1). Radical surgical resection and adjuvant chemotherapy (ifosfamide and epirubicin) was evaluated on Survival and tumor recurrence. Radical surgical resection followed by adjuvant chemotherapy with ifosfamide and epirubicin resulted in 9-month survival without recurrence in a patient with a rare intimal aortic sarcoma.
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