Why the study?
Does apixaban resolve de novo ascending aortic thrombus in a patient without associated aortic pathology?
Does apixaban resolve de novo ascending aortic thrombus in a patient without associated aortic pathology?
Apixaban may be an effective medical therapy for the resolution of de novo ascending aortic mural thrombus, avoiding the need for surgical intervention.
Apixaban may resolve de novo ascending aortic thrombus without surgery; hypothesis-generating case report requiring prospective confirmation.
An ascending aortic thrombus is a rare source for embolic transient ischemic attack (TIA) or stroke without an associated aortic pathology. Here we describe a case of a patient who presented with generalized symptoms of headache and fatigue who, on subsequent work-up , was found to have an ascending aortic thrombus with no obvious associated aortic pathology, and was successfully treated with apixaban, a newer direct oral anticoagulant.
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Houmsse et al. (2018) studied this question.
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