Key result
Spinal anesthesia significantly reduced the odds of a 1-minute Apgar score less than seven compared to general anesthesia (OR 0.24) in neonates delivered by cesarean section.
Why the study?
Does regional anesthesia improve neonatal outcomes in ASA I-II term pregnant women undergoing cesarean section compared to general anesthesia?
Population
782 ASA I-II term pregnant women with no fetal distress and abnormality coming for elective or emergency…
Comparison
Regional anesthesia vs General anesthesia
Design
Meta-analysis, Randomized controlled trials
Follow-up
up to 24 hours
Authors
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Supports preferring spinal over general anesthesia for cesarean delivery to improve neonatal Apgar scores; reinforces Level 1 evidence favoring regional anesthesia.
Systematic Review (n=782)
Does regional anesthesia improve neonatal outcomes in ASA I-II term pregnant women undergoing cesarean section compared to general anesthesia?
Odds Ratio: 0.24 (95% CI 0.14–0.42)
Regional anesthesia is associated with better 1-minute Apgar scores and 5-minute mean Apgar scores compared to general anesthesia for cesarean sections.
Mekonnen et al. (2016) conducted a systematic review in Pregnancy requiring cesarean section (n=782). Regional Anesthesia (Spinal/Epidural) vs. General Anesthesia was evaluated on Apgar score at one minute less than seven (OR 0.24, 95% CI 0.14 to 0.42). Spinal anesthesia significantly reduced the odds of a 1-minute Apgar score less than seven compared to general anesthesia (OR 0.24) in neonates delivered by cesarean section.
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