Key result
Male sex was associated with a higher risk of subsequent interventions at the coarctation site or related structures in adults with repaired coarctation of the aorta (HR 1.6; 95% CI 1.2-2.2).
Why the study?
Coarctation of the aorta coexists with cardiac anomalies and long-term complications requiring reintervention, but the prevalence, risk factors for late interventions, and late mortality needed clarification.
Cohort (n=683)
Yes
Hazard Ratio: 1.6 (95% CI 1.2–2.2)
In adults with repaired coarctation of the aorta, subsequent interventions are common (affecting 29% of patients) and late mortality is increased, highlighting the need for long-term surveillance.
No takes yet. Share an insight, caveat, or question.
Supports sex-stratified surveillance in repaired coarctation; leaves open prospective validation of tailored protocols.
Blylod et al. (2022) conducted a cohort in Repaired coarctation of the aorta (n=683). Male sex vs. Female sex was evaluated on Intervention at the coarctation site, aortic valve, left ventricular outflow tract, or ascending aorta (HR 1.6, 95% CI 1.2-2.2). Male sex was associated with a higher risk of subsequent interventions at the coarctation site or related structures in adults with repaired coarctation of the aorta (HR 1.6; 95% CI 1.2-2.2).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: