Understanding the underlying mechanisms of electrical storm, particularly sympathetic activation and calcium overload, is crucial for developing targeted therapies like sympathetic denervation and CaMK II inhibitors.
lectrical storm (ES) is defined as 3 or more episodes of sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) within 24 hours.1) ES is experienced by 10-58% of patients with an implantable cardioverter-defibrillator (ICD) for secondary prevention and 4-7% for primary prevention.2,3) ES is not only a risk factor of sudden death but also a strong predictor of poor long-term outcomes, including high mortality and morbidity for patients with ICD.2,4)
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Kani et al. (2021) conducted an editorial in Electrical Storm. Electrical storm management was evaluated.
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