What question did this study set out to answer?

To review the latest trends in salivary research and evaluate the diagnostic, prognostic, and therapeutic monitoring utility of saliva in health and disease.

January 1, 2015Biochemia MedicaOpen Access

Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid: a systematic review

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Authors

LNLázaro Alessandro Soares NunesUniversidade Estadual de Campinas (UNICAMP)SMSayeeda MussaviraCluster University Srinagar

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Implication

Systematic review reveals the diagnostic and monitoring utility of saliva in oral and systemic diseases, highlighting the need to standardize collection and analysis.

Key Points

To review the latest trends in salivary research and evaluate the diagnostic, prognostic, and therapeutic monitoring utility of saliva in health and disease.
Conducted a systematic review of salivary research and analytical advancements published over the past two decades.
Evaluated salivary diagnostic kits, systems biology approaches, and sample handling protocols.
Demonstrated that salivary biomarkers reflect diverse physiological and pathological conditions, enabling non-invasive health monitoring, disease diagnosis, and drug monitoring.
Identified critical clinical translation hurdles related to pre-analytical and analytical variability, particularly circadian fluctuation, sample collection and storage protocols, and contamination risks.

Cite This Study

Nunes et al. (2015) studied this question.

synapsesocial.com/papers/6a9ecb8613a83e4d34b28b3e https://doi.org/10.11613/bm.2015.018

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Implication

Systematic review reveals the diagnostic and monitoring utility of saliva in oral and systemic diseases, highlighting the need to standardize collection and analysis.

Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid: a systematic review

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid: a systematic review

Discussion

Member takes

Implication

Key Points

Cite This Study

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