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A method has been developed for calculating the biological equivalent dose distribution for pion beams which is computationally simple enough to be used in routine treatment planning. Dose distributions calculated for the irradiation of simple target volumes, using a conventional single port rectangular beam geometry and using a multiport cylindrical geometry which approximates the configuration of the Stanford pion channel, illustrate the inherent advantages of the multiport irradiation in decreasing the entrance dose and in reducing variations in the pion star fraction (pion star dose/total dose) across the target volume. It is also shown that by scanning in two dimensions the dose distribution can be made to conform to an arbitrary target volume.
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Li et al. (1974) studied this question.
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