Key result
Prophylactic diltiazem given 24 to 48 hours after admission reduced the incidence of early reinfarction and severe angina in patients with non-Q-wave myocardial infarction.
Why the study?
Does prophylactic diltiazem reduce early reinfarction and severe angina in patients with non-Q-wave myocardial infarction?
Does prophylactic diltiazem reduce early reinfarction and severe angina in patients with non-Q-wave myocardial infarction?
Prophylactic diltiazem administered early after non-Q-wave myocardial infarction reduces the risk of early reinfarction and severe angina.
Although mortality in the first month after myocardial infarction is only 8% for patients who have non-Q-wave infarction, these patients are highly vulnerable to reinfarction and death throughout most of the first year. Repeated episodes of non-Q-wave infarction result in a cumulative amount of injury so that two years after the initial episode, survival rates of these patients are similar to those of patients with Q-wave infarction. Prophylactic diltiazem (Cardizem) given 24 to 48 hours after admission reduced the incidence of early reinfarction and severe angina in patients who had non-Q-wave infarction.
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Robert Roberts (1988) conducted a review in non-Q-wave myocardial infarction. Prophylactic diltiazem (Cardizem) was evaluated on early reinfarction and severe angina. Prophylactic diltiazem given 24 to 48 hours after admission reduced the incidence of early reinfarction and severe angina in patients with non-Q-wave myocardial infarction.
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