Key result
Two children with structurally normal hearts survived neonatal myocardial infarction, with hypercholesterolemia and subsequent thrombosis postulated as the likely cause.
Case Report (n=2)
This report highlights rare cases of survival following neonatal myocardial infarction and suggests a potential role for hypercholesterolemia in its pathogenesis.
Alerts clinicians to rare neonatal MI survival in normal hearts; case report leaves open hypercholesterolemia role and requires confirmation.
These are case reports of two children with structurally normal hearts and with normal coronary arteries, who survived myocardial infarction in the early neonatal period. They are only the third and fourth reported survivors of neonatal myocandial infarction and the first in which hypercholesterolemia is postulated to have played an important role. The most likely cause of the myocardial infarction was thrombosis or thromboembolism. Changes in hemostatic function associated with hypencholesterolemia may be relevant.
No takes yet. Share an insight, caveat, or question.
Boulton et al. (1991) conducted a case report in Neonatal myocardial infarction (n=2). Hypercholesterolemia was evaluated on Survival after neonatal myocardial infarction. Two children with structurally normal hearts survived neonatal myocardial infarction, with hypercholesterolemia and subsequent thrombosis postulated as the likely cause.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: