Key result
Neonatal myocardial infarction can occur in infants with normal hearts and coronary arteries, most frequently caused by coronary artery occlusion secondary to paradoxical thromboembolization.
Case Report (n=2)
Myocardial infarction should be considered in the differential diagnosis of newborns presenting with acute shock, warranting an ECG even if the heart and coronary arteries are structurally normal.
Clinicians should consider myocardial infarction in distressed newborns; this case series leaves open optimal diagnostic and therapeutic strategies.
Myocardial infarction is rarely recognized in the newborn. We report two cases in which the infant had a normal heart with normal coronary arteries. A review of previously described cases suggests that the most frequent cause of neonatal myocardial infarction is coronary artery occlusion secondary to paradoxical thromboembolization. It is speculated that infarction also can result from coronary hypoperfusion in asphyxiated infants. This report serves to remind the clinician that myocardial infarction can occur in the neonatal period and that an ECG should be obtained when evaluating a newborn with acute onset of shock.
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MAJ Howard Kilbride (1980) conducted a case report in Neonatal myocardial infarction (n=2). Paradoxical thromboembolization or coronary hypoperfusion was evaluated on Cause of neonatal myocardial infarction. Neonatal myocardial infarction can occur in infants with normal hearts and coronary arteries, most frequently caused by coronary artery occlusion secondary to paradoxical thromboembolization.
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