Key result
Myocardial infarction patients exhibited significantly lower mean Sobolev norms (0.168) compared to healthy controls (0.273) when analyzed using the novel 3D phase diagram technique.
Cross-Sectional (n=15)
A novel 3D phase diagram technique for vectorcardiogram analysis can statistically differentiate between healthy controls and patients with myocardial infarction based on energy-related parameters.
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3D phase diagram analysis may differentiate MI cases; hypothesis-generating and requires prospective validation before clinical adoption.
The article is intended to propose the new technique for analysis and visualization of vectorcardiograms based on the 3D phase diagrams. The regular Frank 3D lead system was considered as the signal source to construct 3D vector space. The three cardio signals from the lead system, representing the currents in the body, and the three integrated in time signals, representing the corresponding charge flows, were used to form 3D phase diagram. This diagram is considered as a new compact description of the dipole object properties in the 3D space, combining simultaneously information about the charge movements and the changes in values and orientation of the current. The regular properties, like the angular momentum of the charge flow and the dipole strength vectors and their covariance can be evaluated from the real vectorcardiogram. Based on the set of vectorcardiograms for 8 healthy controls and 7 myocardial infarction patients the 3D phase diagrams and their statistical parameters are evaluated and discussed. An example is given of the technique implementation for the comparison of the 3D phase diagrams in a control and a myocardial infarction patient.
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Valeri Goussev (2016) conducted a cross-sectional in Myocardial infarction (n=15). Myocardial infarction vs. Healthy controls was evaluated on Mean Sobolev norms (Ψ0) (p=<0.05). Myocardial infarction patients exhibited significantly lower mean Sobolev norms (0.168) compared to healthy controls (0.273) when analyzed using the novel 3D phase diagram technique.
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