Key result
Regularly-timed pacing stimuli during ventricular fibrillation significantly increased local spatial organization, indicating VF is a high-dimensional response with changing spatial coherence.
Why the study?
Does regularly-timed pacing capture fibrillating myocardium and alter spatial organization during ventricular fibrillation in pig hearts?
Does regularly-timed pacing capture fibrillating myocardium and alter spatial organization during ventricular fibrillation in pig hearts?
Ventricular fibrillation exhibits high-dimensional spatial coherence that evolves over time and can be locally organized by regularly-timed pacing.
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Pacing may locally organize VF in animal models; leaves open translation to human defibrillation strategies.
Bayly et al. (1998) studied ventricular fibrillation. regularly-timed pacing stimuli was evaluated on spatial organization and predictability. Regularly-timed pacing stimuli during ventricular fibrillation significantly increased local spatial organization, indicating VF is a high-dimensional response with changing spatial coherence.
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