Key result
Video-assisted mitral valve replacement resulted in significantly smaller wound lengths (5.33 cm vs 7.08 cm, P<0.001) and lower early postoperative pain compared to right anterior mini-thoracotomy.
Why the study?
Minimally invasive mitral valve surgery reduces potential sternal complications with favorable aesthetics, but operative and short-term postoperative outcomes needed evaluation comparing video-assisted versus right anterior thoracotomy approaches.
Does video-assisted mitral valve replacement improve perioperative outcomes and reduce pain compared to right anterior mini-thoracotomy in patients undergoing isolated mitral valve replacement?
Observational (n=40)
No
Does video-assisted mitral valve replacement improve perioperative outcomes and reduce pain compared to right anterior mini-thoracotomy in patients undergoing isolated mitral valve replacement?
Absolute Event Rate: 5.33% vs 7.08%
p-value: p=<0.001
Video-assisted mitral valve replacement is a safe and feasible alternative to right anterior mini-thoracotomy, offering significantly smaller incisions and reduced early postoperative pain with comparable surgical and echocardiographic outcomes.
VAMVR may yield smaller wounds and less early pain than ATMVR; leaves open clinical superiority pending randomized trials.
Background Minimally invasive mitral valve surgery has been introduced as a safe alternative to full sternotomy through smaller chest wall incisions to reduce the potential sternal complications in addition to the favorable aesthetic effect. This observational study has been designed to evaluate and compare operative and short-term postoperative outcomes of video-assisted versus right anterior thoracotomy mitral valve replacement. The study was conducted on 40 cases and divided into two groups: group 1, comprised of 20 patients who underwent video-assisted mitral valve replacement (VAMVR), and group 2, comprised of 20 patients who underwent right anterior mini-thoracotomy mitral valve replacement (ATMVR). Preoperative data, intraoperative procedures, and early postoperative results have been compared between both techniques. Results Intraoperative parameters showed no statistical difference between the two groups. Wound length in the VAMVR group was statistically smaller than the ATMVR group, 5.33 ± 0.96 cm versus 7.08 ± 1.24 cm, respectively (P < 0.001). The intraoperative assessment by TEE showed a well-suited, well-functioning prosthetic valve, and no paravalvular leak in the two groups. In both groups, there were statistically significant reductions in left ventricular end diastole, left atrial diameter, and pulmonary artery systolic pressure in the 3-month postoperative ECHO in comparison to the preoperative ECHO (P < 0.001). There was a statistically significant decrease in left ventricular end-systole in the VAMVR group in the 3-month postoperative ECHO in comparison to the preoperative ECHO (P < 0.001). ICU visual analog scale (VAS) was significantly lower in the VAMVR group than in the ATMVR group (P = 0.049). There was a gradual reduction in VAS in both groups along the period of 3 months postoperatively without significant differences between the two groups in 2 weeks and 3 months postoperatively. Conclusions VAMVR and ATMVR could be considered safe, feasible approaches with favorable perioperative surgical and echocardiographic results. VAMVR showed statistically significant smaller wounds and less postoperative pain than ATMVR, which may offer potential advantages in terms of reduced postoperative discomfort and cosmetic appearance for the thoracoscopic technique. Further randomized studies with larger cohorts and longer follow-ups are recommended to evaluate the long-term benefits and safety of both techniques.
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Awad et al. (2025) conducted an observational in Mitral valve disease (n=40). Video-assisted mitral valve replacement (VAMVR) vs. Right anterior mini-thoracotomy mitral valve replacement (ATMVR) was evaluated on Wound length (p=<0.001). Video-assisted mitral valve replacement resulted in significantly smaller wound lengths (5.33 cm vs 7.08 cm, P<0.001) and lower early postoperative pain compared to right anterior mini-thoracotomy.
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