Radiofrequency Ablation of a Tumor Causing Oncogenic Osteomalacia

mice had a significant increase in plasma homocysteine levels (P<0.05, by analysis of variance with Tukey's post hoc multiple-comparison test).In contrast, plasma homocysteine levels in the oxidatively stressed APOE-/-and APOE ε4 mice remained unchanged from values obtained in the presence of dietary folate.These results provide evidence that plasma homocysteine may be an accurate predictor of folate deficiency under otherwise normal conditions but may not reflect folate deficiency in the presence of underlying risk factors known to promote increased oxidative stress.In the future, an accompanying test or series of tests to assess the degree of cellular oxidative stress may be warranted in order to interpret plasma homocysteine values correctly.