Key result
High-degree heart block occurs in up to 8.3% of acute lymphocytic myocarditis cases and 23% to 30% of cardiac sarcoidosis cases, which may warrant early immunosuppression.
Why the study?
When should high-grade heart block trigger a search for a treatable cardiomyopathy?
When should high-grade heart block trigger a search for a treatable cardiomyopathy?
Answers are grounded in this paper and cite their sources.
High-grade heart block can be a manifestation of treatable cardiomyopathies like cardiac sarcoidosis and giant cell myocarditis, where early immunosuppression may improve outcomes.
heart block is an uncommon manifestation of acute myocarditis in adults. The rate of heart block requiring a pacemaker in biopsy-proven acute lymphocytic myocarditis generally is low but has been reported in up to 8.3% of cases. 1 Important exceptions include cardiac sarcoidosis and giant cell myocarditis (GCM), 2 uncommon and idiopathic disorders for which early immunosuppression may improve clinical outcomes. High-degree heart block occurs in the course of biopsy-proven cardiac sarcoidosis in 23% to 30% of cases (Table ).
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Cooper et al. (2011) conducted an editorial in Acute myocarditis, cardiac sarcoidosis, and giant cell myocarditis. Treatable cardiomyopathies (cardiac sarcoidosis and giant cell myocarditis) was evaluated. High-degree heart block occurs in up to 8.3% of acute lymphocytic myocarditis cases and 23% to 30% of cardiac sarcoidosis cases, which may warrant early immunosuppression.
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