Hybrid Schwannoma of the Nasal Cavity: A Rare Case Report with Literature Review

Sinonasal schwannomas are extremely rare, comprising only 4% of all head and neck schwannomas. Their atypical location and nonspecific symptoms often result in delayed diagnosis. This case highlights a rare hybrid schwannoma in the right nasal cavity of a young female, contributing to the limited literature on sinonasal nerve sheath tumors. A 27-year-old female presented with a one-year history of right-sided nasal obstruction, rhinorrhea, and recurrent epistaxis. Examination revealed a polypoidal mass in the right nasal cavity. Laboratory investigations showed mild anemia and an elevated white cell count. Imaging identified a soft tissue mass with no bone erosion or intracranial involvement. The patient underwent Functional Endoscopic Sinus Surgery (FESS), and histopathological analysis confirmed a hybrid nerve sheath tumor (70% schwannoma, 30% neurofibroma) with positive staining for S-100 and CD34. Postoperative MRI showed no residual or recurrent mass. This case underlines the importance of considering rare neural tumors in the differential diagnosis of nasal masses. Early surgical intervention with histological confirmation ensures favorable outcomes and prevents complications associated with delayed treatment.