Key result
Prior percutaneous coronary intervention did not significantly affect in-hospital mortality in patients undergoing coronary artery bypass grafting compared to those without prior intervention (4.5% vs 3.7%, p=0.370).
Why the study?
PCI is a crucial treatment for coronary artery disease, but the impact of prior PCI on subsequent CABG outcomes needed evaluation.
Does prior percutaneous coronary intervention increase in-hospital mortality or morbidity in patients undergoing coronary artery bypass grafting?
Cross-Sectional (n=2,579)
No
Does prior percutaneous coronary intervention increase in-hospital mortality or morbidity in patients undergoing coronary artery bypass grafting?
Absolute Event Rate: 4.5% vs 3.7%
p-value: p=0.370
Prior PCI does not significantly increase in-hospital mortality for patients subsequently undergoing CABG, though it is associated with a higher risk of post-operative atrial fibrillation.
Prior PCI should not yet alter CABG risk assessment; leaves open its association with post-operative AF for prospective study.
Percutaneous coronary intervention (PCI) is a crucial treatment for patients with coronary artery disease (CAD), especially high-risk patients like advanced age, diabetes, chronic kidney disease, left main lesions, and multi vessel CAD. Objective: To compare coronary artery bypass grafting outcomes in patients with and without prior percutaneous coronary artery intervention. Methods: This retrospective 5-year cross-sectional study was conducted on 2579 patients operated for CABG in between August 1st, 2017, and December 31st, 2021 in a tertiary care hospital. All patients who underwent CABG were included in study, and comparison was done in patients with or without PCI. Data analysis were done by using SPSS version 23. p<0.05 was set statistically significant. Results: The results of perfusion and cross clamp time in operative room, use of IABP and reopening rates in both groups showed no statistically significant difference. The incidence of post-operative atrial fibrillation in group A is 4% Vs 1.5% in group B with significant p value of 0.028. Prolong ventilation, perioperative stroke and reintubation rates comparison in both groups were with non-significant p values. In hospital mortality was 4.5% in group A and 3.7% in group B with p-value of 0.370 which is non-significant. Conclusions: Patients with prior percutaneous coronary intervention can undergo CABG surgery with similar mortality rates as those with no prior PCI. The only significant difference in morbidity is post-operative risk of atrial fibrillation which is more in prior PCI patients’ group.
No takes yet. Share an insight, caveat, or question.
Meenal Sikander Khan (2023) conducted a cross-sectional in Coronary Artery Disease (n=2,579). Prior percutaneous coronary intervention vs. No prior percutaneous coronary intervention was evaluated on In-hospital mortality (p=0.370). Prior percutaneous coronary intervention did not significantly affect in-hospital mortality in patients undergoing coronary artery bypass grafting compared to those without prior intervention (4.5% vs 3.7%, p=0.370).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: