Key result
A 46-year-old man with cerebral palsy developed a rapidly progressive 24x13 cm angiosarcoma in his left thigh, which metastasized to bone and led to death 13 months after onset despite multimodal treatment.
Case Report (n=1)
This case report highlights the rapid progression and poor prognosis of thigh angiosarcoma, complicated by delayed diagnosis due to atypical presentation and underlying cerebral palsy.
Alerts clinicians to dismal prognosis of thigh angiosarcoma in cerebral palsy despite treatment; leaves open optimal early detection strategies.
We report a case of angiosarcoma in a 46-year-old man with cerebral palsy. He had difficulty walking caused by the rapid growth of a tumor mass in his left posterior thigh. The tumor was 24×13cm in size, and was an elastic soft mass giving off local heat. Magnetic resonance imaging and computed tomography showed multivacuoles in the semitendinous muscle and semimembranous muscle with signs of compression of muscle and blood vessels. After biopsy granulation was seen, with bleeding from the wound continuling leading to enucleation of the tumor mass. The pathological diagnosis after surgery was angiosarcoma. Local recurrence occurred post-operatively Note to Anther one-half what (days, months). After wide resection of local tumor, the patient was treated with chemotherapy, radiotherapy and immunotherapy. Multiple metastases to bone occurred eight months later and the patient died thirteen months from onset.
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Abe et al. (1997) conducted a case report in Angiosarcoma of the thigh (n=1). Wide resection, chemotherapy, radiotherapy, and immunotherapy was evaluated on Clinical course and survival. A 46-year-old man with cerebral palsy developed a rapidly progressive 24x13 cm angiosarcoma in his left thigh, which metastasized to bone and led to death 13 months after onset despite multimodal treatment.
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