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July 4, 2013Cancer Research

JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

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Authors

PKPaula KroonAstraZeneca (Netherlands)PBPaul A. BerryDoctors Hospital at RenaissanceMSMichael J. StowerNational Health Service

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Kroon et al. (2013) studied this question.

synapsesocial.com/papers/6a9efaf2f582ac9ac1904ef3https://doi.org/10.1158/0008-5472.can-13-0874
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulation of growth of prostate cancer cells selected in the presence of interleukin-6 by the anti-interleukin-6 antibody CNTO 3282006 · 39 citations
  2. 2Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer1999 · 281 citations
  3. 3Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue2000 · 172 citations
  4. 4TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway1995 · 1,832 citations