Key result
Electron-beam therapy yielded a good initial response in a 77-year-old woman with scalp angiosarcoma, but extensive local recurrence and distant metastases developed after seven months.
Case Report (n=1)
Angiosarcoma should be considered in the differential diagnosis of scarring alopecia of the scalp in elderly patients.
Scalp angiosarcoma merits consideration in elderly scarring alopecia; this case leaves open durable treatment options beyond transient radiation response.
• Angiosarcoma with initial involvement of the scalp is a rare, malignant neoplasm. We present the case of a 77-year-old woman in whom extensive scarring alopecia developed that was proved histologically to be due to angiosarcoma. She had a good initial response to treatment with electron-beam therapy, but after seven months, extensive nodules and indurated areas on the face beyond the borders of the radiation field developed. Subsequently, massive cervical adenopathy and metastases to the lungs, liver, and spleen developed. Angiosarcoma must be differentiated from other malignant blood vessel tumors and should be considered in the differential diagnosis of scarring alopecia of the scalp in elderly patients. (Arch Dermatol116:683-686, 1980)
No takes yet. Share an insight, caveat, or question.
T. E. Knight (1980) conducted a case report in Angiosarcoma of the scalp presenting as scarring alopecia (n=1). Electron-beam therapy was evaluated on Clinical response and disease progression. Electron-beam therapy yielded a good initial response in a 77-year-old woman with scalp angiosarcoma, but extensive local recurrence and distant metastases developed after seven months.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: