What question did this study set out to answer?

Investigate the synthesis, isolation, and structural properties of 4,6-O-butylidene acetal derivatives prepared from D-glucose and D-glucitol.

January 1, 1965Journal of the Chemical Society (Resumed)

The 4,6-O-butylidene acetals of D-glucose and D-glucitol

View Full Paper

Ask AI

Bookmark

Authors

TBT. G. BonnerSt. John's University EBE. J. BourneRoyal Holloway University of London DLDustin A. LewisHarvard University

Discussion

Member takes

Implication

Chemical synthesis demonstrates the formation of 4,6-O-butylidene acetals from D-glucose and D-glucitol, highlighting regioselective methods for carbohydrate modification.

Key Points

Investigate the synthesis, isolation, and structural properties of 4,6-O-butylidene acetal derivatives prepared from D-glucose and D-glucitol.
Conducted acid-catalyzed condensation reactions between butyraldehyde and parent hexoses (D-glucose and D-glucitol).
Isolated and structurally characterized the resulting cyclic acetal derivatives to verify regioselective protection at positions 4 and 6.
Demonstrated successful synthesis of stable 4,6-O-butylidene acetal rings on both D-glucose and D-glucitol frameworks.
Confirmed regiochemical preference for cyclic acetal formation bridging the C-4 and C-6 hydroxyl groups.

Cite This Study

Bonner et al. (1965) studied this question.

synapsesocial.com/papers/6a9efce130f3e6e092fd53f7 https://doi.org/10.1039/jr9650007453

View Full Paper

Ask AI

Bookmark

Implication

Chemical synthesis demonstrates the formation of 4,6-O-butylidene acetals from D-glucose and D-glucitol, highlighting regioselective methods for carbohydrate modification.

The 4,6-O-butylidene acetals of D-glucose and D-glucitol

Discussion

Member takes

Implication

Key Points

Cite This Study

The 4,6-O-butylidene acetals of D-glucose and D-glucitol

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider