Key result
Very young patients (≤35 years) with acute myocardial infarction more frequently presented with anterior wall STEMI, single vessel disease, and better LVEF compared to older patients.
Why the study?
Cardiovascular disease incidence is increasing in very young adults, but these patterns are not well studied in the South East Asian population.
What are the epidemiological and clinical characteristics of very young adults (≤35 years) presenting with acute myocardial infarction compared to older patients?
Case-Control (n=206)
No
What are the epidemiological and clinical characteristics of very young adults (≤35 years) presenting with acute myocardial infarction compared to older patients?
Very young patients (≤35 years) presenting with AMI in India typically have anterior STEMI, single vessel disease, and are predominantly smokers without other traditional risk factors.
May inform smoking prevention in young Indians; leaves open whether features alter management.
BACKGROUND: Cardiovascular disease is the leading cause of death in India. Previously it was thought to be a disease of the elderly but now an epidemiological transition is being seen with increasing incidence in the very young adults as well. Such patterns are not well studied in the South East Asian population. OBJECTIVE: To study the epidemiological profile of very young (≤35 years) adults presenting with an acute myocardial infarction (AMI) in comparison with an older cohort. METHODOLOGY: The present study included all patients presenting with AMI to the emergency or to the out-patient department of the G B Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi between January 2014 and October 2015. A total of 102 subjects ≤35 years with AMI comprised the study subjects (cases) and were compared with 104 subjects >35 years old with AMI (Controls). RESULTS & CONCLUSION: Most of the very young AMI patients presented with an anterior wall ST segment elevation myocardial infarction, a stable hemodynamic profile, single vessel disease and better left ventricular ejection fraction as compared with controls. Most of the patients were from urban and semi-urban areas, middle and lower middle socioeconomic status and were smokers but lacked other traditional risk factors.
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Gupta et al. (2020) conducted a case-control in Acute myocardial infarction (n=206). Very young age (≤35 years) vs. Older age (>35 years) was evaluated on Epidemiological profile and clinical presentation. Very young patients (≤35 years) with acute myocardial infarction more frequently presented with anterior wall STEMI, single vessel disease, and better LVEF compared to older patients.
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