Key result
In young adults, cluster B personality disorders were independently associated with substance use disorders, including daily cigarette smoking and illicit drug use, even after adjusting for other personality disorder clusters.
Why the study?
Is the presence of DSM-IV personality disorders associated with substance use disorders in young adults?
Cross-Sectional (n=1,943)
Is the presence of DSM-IV personality disorders associated with substance use disorders in young adults?
In young adults, Cluster B personality disorders are independently associated with a higher risk of substance use disorders, highlighting a specific comorbidity that warrants clinical attention.
Answers are grounded in this paper and cite their sources.
Supports integrated screening for substance use in young adults with cluster B personality disorders; extends comorbidity data but leaves causality open.
BACKGROUND: There have been no studies of the co-occurrence of personality and substance use disorders in young community-dwelling adults. AIMS: To examine the association between DSM-IV personality disorders and substance use disorders in a large representative sample of young community-dwelling participants. METHOD: Young Australian adults (n=1520, mean age=24.1 years) were interviewed to determine the prevalence of substance use disorders; 1145 also had an assessment for personality disorder. RESULTS: The prevalence of personality disorder was 18.6% (95% CI 16.5-20.7). Personality disorder was associated with indices of social disadvantage and the likely presence of common mental disorders. Independent associations were found between cluster B personality disorders and substance use disorders. There was little evidence for strong confounding or mediating effects of these associations. CONCLUSIONS: In young adults, there are independent associations between cluster B personality disorders and substance use disorders.
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Moran et al. (2006) conducted a cross-sectional in Personality and substance use disorders (n=1,943). Cluster B personality disorders vs. Absence of cluster B personality disorders was evaluated on Daily cigarette smoking (as a representative substance use disorder) (OR 2.6, 95% CI 1.6-4.1, p=<0.001). In young adults, cluster B personality disorders were independently associated with substance use disorders, including daily cigarette smoking and illicit drug use, even after adjusting for other personality disorder clusters.
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