Key result
Anomalous origin of the left coronary artery with severe stenosis or complete occlusion at the ostium caused sudden death during physical exercise in two 12-year-old children.
Case Report (n=2)
Anomalous origin of the left coronary artery with ostial stenosis or occlusion is a congenital anomaly that can cause sudden death in children during physical exercise.
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Rare ostial anomaly linked to exercise sudden death in children; hypothesis-generating for screening and prevention.
Two autopsy cases of anomalous coronary artery were reported. The patients were a schoolgirl and a schoolboy, who died suddenly during physical exercise at the age of twelve. At postmortem examination in both cases the left coronary artery arose at the comissure from aorta, and in one case the left coronary ostium was completely obstructed with fibrous tissue, whereas in the other case it was severely stenotic. The cause of anomalous ostial position should be regarded as congenital, but the complete occlusion and severe stenosis at the orifice seemed to be modified by several factors--both congenital acquired. For the prevention of sudden death caused by this anomaly, cardiac angiography would have been necessary at the outset of anginal pain.
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Murai et al. (1982) conducted a case report in Anomalous origin of the left coronary artery (n=2). Anomalous origin of the left coronary artery was evaluated on Sudden death. Anomalous origin of the left coronary artery with severe stenosis or complete occlusion at the ostium caused sudden death during physical exercise in two 12-year-old children.
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