Key result
Proximal femoral nail antirotation had shorter operative time (p=0.006) and lower blood loss (p<0.0001) than bipolar hemiarthroplasty, which provided better early Harris Hip Scores.
Why the study?
Intertrochanteric fractures carry high one-year mortality in elderly patients, prompting a comparison of proximal femoral nail antirotation versus bipolar hemiarthroplasty for perioperative and functional outcomes.
Does Proximal Femoral Nail Antirotation compared to bipolar hemiarthroplasty improve surgical and functional outcomes in elderly patients with intertrochanteric fractures?
Meta-Analysis (n=495)
Does Proximal Femoral Nail Antirotation compared to bipolar hemiarthroplasty improve surgical and functional outcomes in elderly patients with intertrochanteric fractures?
p-value: p=0.006
PFNA and bipolar hemiarthroplasty offer comparable overall results for intertrochanteric fractures in the elderly, with PFNA providing better surgical metrics and hemiarthroplasty offering faster early functional recovery.
Clinicians should weigh PFNA's surgical advantages against hemiarthroplasty's early recovery benefits; extends Level 1 evidence on short-term trade-offs.
Introduction Intertrochanteric fractures account for almost half of all hip fractures, with a mortality rate of 15 to 20 % within one year following fracture, primarily in elderly patients aged 65 years old and older. The purpose of this study is to compare the operative time, intraoperative blood loss, intraoperative blood transfusion, hospitalization time, weight-bearing time, Harris Hip Score at 1, 3, 6, 12 months follow-up, and complications after proximal femoral nail antirotation versus bipolar hemiarthroplasty for intertrochanteric fracture in elderly patients based on the published literature of their comparison. Methods We conducted a comprehensive search in the electronic databases such as PubMed, Scopus, and Google Scholar. Original articles up to November 2024 were screened, focusing on retrospective or prospective cohort studies. Results and Discussion The initial search yielded 702 studies. Six cohort studies with a total of 495 participants were assessed. The Proximal Femoral Nail Antirotation (PFNA) showed statistically significant shorter operative time (p = 0.006), lower intraoperative blood loss (p < 0.0001) compared with bipolar hemiarthroplasty. Bipolar Hemiarthroplastty had statistically significant better Harris Hip Score at 1 and 3 month follow-up post-operatively (p < 0.00001), (p = 0.001). It provides early weight-bearing (p = 0.003) and helps mobilize post-operative patients. Blood transfusion, hospitalization time, Harris Hip Score after 6- month follow-up, and complications had balanced results between two apporaches. Conclusion PFNA and bipolar Hemiarthroplasty have comparable results in intertrochateric fractures in the elderly. PFNA has the advantages of shorter operative time, and lower intraoperative blood loss. Bipolar hemiarthroplasty has the advantages of better Harris Hip Score at 1 and 3 month follow-up and earlier weight-bearing. Level of Evidence: I.
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Wijaya et al. (2025) conducted a meta-analysis in Intertrochanteric fractures (n=495). Proximal femoral nail antirotation (PFNA) vs. Bipolar hemiarthroplasty was evaluated on Operative time (p=0.006). Proximal femoral nail antirotation had shorter operative time (p=0.006) and lower blood loss (p<0.0001) than bipolar hemiarthroplasty, which provided better early Harris Hip Scores.
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