What question did this study set out to answer?

To evaluate the diagnostic performance of bedside lung ultrasound in the early identification of ventilator-associated pneumonia and assess sonographic predictors of patient mortality.

November 13, 2025Egyptian Journal of BronchologyOpen Access

Role of transthoracic ultrasound in early diagnosis of ventilator-associated pneumonia

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Authors

RSRagia Samir SharsharTanta University DEDalia Ezzat El-ShaarawyTanta University MEMohamed Gamal A. ElkholyTanta University

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Implication

Observational study reveals superior diagnostic detection of pneumonia in mechanically ventilated patients, indicating greater bedside utility than radiography.

Key Points

To evaluate the diagnostic performance of bedside lung ultrasound in the early identification of ventilator-associated pneumonia and assess sonographic predictors of patient mortality.
Conducted a prospective observational longitudinal study of N=40 mechanically ventilated patients with suspected ventilator-associated pneumonia in an intensive care unit at Tanta University Hospitals in Egypt.
Categorized participants based on initial radiological findings into a ventilator-associated tracheobronchitis group (n=9, no radiological changes) and a ventilator-associated pneumonia group (n=31, visible radiological changes).
Compared diagnostic sensitivity between chest ultrasound and chest X-ray at the time of clinical suspicion and evaluated mortality predictors using multivariate logistic regression.
At the onset of clinical suspicion, chest ultrasound demonstrated a significantly higher detection rate of pneumonia-related changes compared to chest X-ray (67.7% vs. 35.5%, P=0.01).
Multivariate logistic regression revealed that a PaO2/FiO2 ratio below 240, bilateral opacity on chest radiograph, and ultrasound-detected pleural effusion were independently associated with increased mortality.
Gram-negative bacteria, predominantly Klebsiella species, were identified as the most frequent causative pathogens isolated from patients with ventilator-associated pneumonia.

Cite This Study

Sharshar et al. (2025) studied this question.

synapsesocial.com/papers/6a9f5fae22052d0ba768fff8 https://doi.org/10.1186/s43168-025-00463-6

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Implication

Observational study reveals superior diagnostic detection of pneumonia in mechanically ventilated patients, indicating greater bedside utility than radiography.

Role of transthoracic ultrasound in early diagnosis of ventilator-associated pneumonia

Discussion

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Implication

Key Points

Cite This Study

Role of transthoracic ultrasound in early diagnosis of ventilator-associated pneumonia

Discussion

Member takes

Implication

Key Points

Cite This Study

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