SARS-CoV and MERS-CoV's effects on the central nervous system & implications for SARS-CoV-2, multiple viruses have been proven to penetrate the CNS, despite the fact that few viruses are particularly neurotropic in nature.Neuroinvasive qualities and neurovirulent features are two ways viruses might be categorized.SARS-CoV-2 caused illness is most commonly associated with respiratory symptoms, there is growing evidence that the SARS-CoV-2 virus, like other known human coronaviruses (SARS-CoV and MERS-CoV), can cause neurological symptoms as a result of both neuroinvasive and neurovirulent mechanisms.However, case studies and series have provided the majority of evidence on the neurological effects of SARS-CoV-2 infection.Although the pathogenesis of COVID-19's neurological effects is unknown, numerous possibilities have been proposed, including direct viral infection of the nervous system, autoimmune sequalae, hypoxia-mediated injury and sequinedmediated harm.Evidence with other human coronaviruses, such as those implicated in the Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) pandemics, provides preliminary evidence for the possibility of SARS-CoV-2 having a neurological impact.SARS is a coronavirus that is prevalent in the CNS and is linked to a variety of neurological illnesses.It is caused by a coronavirus that has a high genetic similarity to SARS-CoV-2.It should be highlighted, however, that case studies with a small sample size are also used to study the neurological implications of the SARS virus.
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Saravanakumar Kasimbedu (2022) studied this question.
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