Key result
End-stage renal disease was not associated with a significant difference in in-hospital mortality during hospitalizations for hypertensive emergency (OR 0.94), but increased the odds of cardiac arrest and acute pulmonary edema.
Why the study?
Although the prevalence and incidence of ESRD are increasing, data on inpatient outcomes of hypertensive emergencies in patients with ESRD are lacking.
Does end-stage renal disease worsen in-hospital outcomes in patients admitted for hypertensive emergency?
Population
105,565 hospitalizations for hypertensive emergency
Comparison
Patients with ESRD vs without ESRD
Design
Retrospective propensity score-matched study using the National Inpatient Sample
Authors
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ESRD patients hospitalized for hypertensive emergency face higher cardiac arrest and pulmonary edema risks; leaves open whether targeted strategies improve outcomes.
Observational (n=105,565)
Yes
Does end-stage renal disease worsen in-hospital outcomes in patients admitted for hypertensive emergency?
Odds Ratio: 0.94 (95% CI 0.46–1.9)
Absolute Event Rate: 0.5% vs 0.47%
p-value: p=0.86
Patients with end-stage renal disease admitted for hypertensive emergency have significantly higher risks of cardiac arrest, acute pulmonary edema, and longer hospital stays compared to those without ESRD.
Park et al. (2022) conducted an observational in Hypertensive emergency (n=105,565). End-stage renal disease (ESRD) vs. Without end-stage renal disease was evaluated on In-hospital mortality (OR 0.94, 95% CI 0.46-1.90, p=0.86). End-stage renal disease was not associated with a significant difference in in-hospital mortality during hospitalizations for hypertensive emergency (OR 0.94), but increased the odds of cardiac arrest and acute pulmonary edema.
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