What question did this study set out to answer?

To compare cognitive impairment, neuropsychiatric symptoms, and general symptomatology between patients with ME/CFS and post-COVID-19 condition, and to examine whether olfactory impairment correlates with cognitive decline.

December 6, 2022Journal of Translational MedicineOpen Access

Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder?

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Authors

NANaiara AzcueBioCruces Health research Institute JGJuan Carlos Gómez‐EstebanUniversity of the Basque Country MAM. AceraBioCruces Health research Institute

Discussion

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Implication

Observational study reveals overlapping cognitive deficits and fatigue in post-COVID-19 condition and chronic fatigue syndrome, suggesting shared mechanisms with greater severity in ME/CFS.

Key Points

To compare cognitive impairment, neuropsychiatric symptoms, and general symptomatology between patients with ME/CFS and post-COVID-19 condition, and to examine whether olfactory impairment correlates with cognitive decline.
Assessed 42 patients with ME/CFS and 73 patients with post-COVID-19 condition.
Evaluated fatigue, sleep quality, anxiety, depression, symptom severity, olfactory function, and multiple cognitive domains across both cohorts.
Sustained attention and processing speed were impaired in 83.3% and 52.4% of ME/CFS patients compared to 56.2% and 41.4% of post-COVID-19 patients, respectively.
ME/CFS patients exhibited statistically significantly worse performance in sustained attention and visuospatial ability compared to post-COVID-19 patients.
Cognitive impairment correlated primarily with physical symptoms and mood in post-COVID-19 condition, whereas anxiety and physical fatigue were primary correlates in ME/CFS.

Cite This Study

Azcue et al. (2022) studied this question.

synapsesocial.com/papers/6a9f80024d9239be3eea383e https://doi.org/10.1186/s12967-022-03764-2

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Implication

Observational study reveals overlapping cognitive deficits and fatigue in post-COVID-19 condition and chronic fatigue syndrome, suggesting shared mechanisms with greater severity in ME/CFS.

Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder?

Discussion

Member takes

Implication

Key Points

Cite This Study

Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder?

Discussion

Member takes

Implication

Key Points

Cite This Study

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