Key result
A 31-year-old woman developed two metachronous cardiac myxomas 7 and 9 years after excision of cutaneous myxomas, highlighting the need for echocardiographic screening in such patients.
Case Report (n=1)
Echocardiographic screening is strongly recommended in patients with histologically diagnosed cutaneous myxomas to detect potentially life-threatening cardiac myxomas associated with this syndrome.
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Hypothesis-generating for screening after cutaneous myxomas; prospective studies needed before practice change.
We report on a 31-year-old woman who underwent surgery for two metachronous cardiac myxomas - 7 and 9 years after excision of several cutaneous myxomas. Our observation is a further case of a syndrome-like complex of cardiac and cutaneous myxoma(s), pigmentation anomalies and endocrine disorders described only recently. As modern investigative methods and the development of cardiovascular surgery have brought about an essential improvement in diagnostics and prognosis of cardiac myxomas, the knowledge of this syndrome-like complex is of great therapeutic importance. Therefore, in our opinion, echocardiographic investigations are strongly recommended even in asymptomatic patients, once several cutaneous myxomas are diagnosed histologically.
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Bier et al. (1989) conducted a case report in Cardiac and cutaneous myxomas (n=1). Echocardiographic screening was evaluated. A 31-year-old woman developed two metachronous cardiac myxomas 7 and 9 years after excision of cutaneous myxomas, highlighting the need for echocardiographic screening in such patients.
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