Key result
Peutz-Jeghers syndrome is associated with a risk of developing gonadal tumors in males, similar to the established risk in females.
This case report highlights that males with Peutz-Jeghers syndrome, like females, are at risk for developing gonadal tumors.
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May warrant gonadal tumor awareness in males with PJS; case-report data leaves open need for confirmatory studies.
The case of a 6-year-old boy with Peutz-Jeghers syndrome (PJS), gynecomastia, and multifocal and bilateral testicular tumors is described. Females with PJS are known to be at increased risk for developing gonadal tumors. This case and other reports from the literature suggest that males, as well as females, with PJS are at risk for developing gonadal tumors.
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Wilson et al. (1986) studied this question. Peutz-Jeghers syndrome is associated with a risk of developing gonadal tumors in males, similar to the established risk in females.
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