Key result
Elderly patients with advanced chagasic cardiopathy had more ventricular premature beats in 24 hours and less functional capacity during exercise testing than young patients.
Why the study?
Does aging worsen cardiovascular function and heart damage in patients with chronic chagasic cardiopathy?
Cross-Sectional
No
Does aging worsen cardiovascular function and heart damage in patients with chronic chagasic cardiopathy?
Elderly patients with advanced Chagas cardiopathy exhibit greater functional impairment and more ventricular arrhythmias than younger patients with similar disease severity.
Supports intensified arrhythmia monitoring in elderly Chagas patients; hypothesis-generating for age-related progression.
The objective of this work was to verify the degree and type of heart damage of elderly chagasic patients seen at an outpatient referral center and to compare them with the changes found in young chagasic patients with a similar degree of heart damage. Elderly and young patients without advanced cardiopathy presented good functional behavior. Elderly patients with advanced cardiopathy had more ventricular premature beats (VPB) in 24 h and less functional capacity in the exercise test than young patients of the same subgroup. There was a higher occurrence of effort-induced VPB and a lower prevalence of severe forms in elderly men, suggesting that Chagas' disease may have a worse evolution in males. The association of cardiac damage characteristic of aging with the secondary damage due to Chagas' disease could explain the greater functional damage found in elderly chagasic patients. Thus, it appears that the physiopathological components of Chagas' disease do have an influence on the clinical course of cardiopathy in the elderly population.
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Rocha et al. (2003) conducted a cross-sectional in Chronic chagasic cardiopathy. Advanced age vs. Young age was evaluated on Degree and type of heart damage including ventricular premature beats and functional capacity. Elderly patients with advanced chagasic cardiopathy had more ventricular premature beats in 24 hours and less functional capacity during exercise testing than young patients.
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