What does this research mean for the field?

Left ventricular diastolic abnormalities, particularly impaired early isovolumic relaxation, are pronounced in early and asymptomatic stages of Chagas's heart disease and may precede systolic compromise. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 1, 1985HeartOpen Access

Echocardiographic features of impaired left ventricular diastolic function in Chagas's heart disease.

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Why the study?

Can digitised echocardiography, phonocardiography, and apexcardiography detect early left ventricular diastolic abnormalities in patients with Chagas's disease?

Population

n=64 subjects, including 20 asymptomatic patients with positive Chagas's serology and no signs of heart…

Comparison

Simultaneous echocardiograms, phonocardiograms… vs Normal subjects and patients with left…

Design

Cross-sectional

Authors

ICI CombellasCentral University of Venezuela JPJuan José PuigbóAcademia Nacional de Medicina HAHarry AcquatellaHospital Clínico Universitario de Caracas

Discussion

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Implication

Early diastolic abnormalities detectable noninvasively in Chagas disease; hypothesis-generating for progression monitoring, needs prospective validation.

Structured PICO

Can digitised echocardiography, phonocardiography, and apexcardiography detect early left ventricular diastolic abnormalities in patients with Chagas's disease?

Population

n=64 subjects, including 20 asymptomatic patients with positive Chagas's serology and no signs of heart disease (group 1), 12 with Chagas's heart disease and symptoms of ventricular arrhythmia but no heart failure (group 2), 20 normal subjects (group 3), and 12 patients with left ventricular hypertrophy (group 4).

Intervention

Simultaneous echocardiograms, phonocardiograms, and apexcardiograms (digitised)

Comparator

Normal subjects and patients with left ventricular hypertrophy

Outcome

Left ventricular isovolumic relaxation time, and the rate and duration of left ventricular cavity dimension increase and wall thinningsurrogate

Digitised echocardiography reveals early isovolumic relaxation and left ventricular diastolic abnormalities in patients with Chagas's disease, which may precede systolic compromise.

Cite This Study

Combellas et al. (1985) studied this question.

synapsesocial.com/papers/6a158cac79ff98d0de4ecc3d https://doi.org/10.1136/hrt.53.3.298

Topics

Echocardiography

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Implication

Early diastolic abnormalities detectable noninvasively in Chagas disease; hypothesis-generating for progression monitoring, needs prospective validation.

Echocardiographic features of impaired left ventricular diastolic function in Chagas's heart disease.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Echocardiographic features of impaired left ventricular diastolic function in Chagas's heart disease.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Topics

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