Cu-MOF/FeOOH Composites Catalyzed Synthesis of Tetrahydrophene Derivatives in Water

制备了Cu-MOF/FeOOH复合材料，并作为催化剂，在水相中对硝基烯和2,5-二羟基-1,4-二噻烷进行了串联环化反应的催化性能研究。以较高产率(最高达98%)合成了系列四氢噻吩类化合物，并对反应放大量实验和催化剂循环再利用进行了系统研究，最后探讨了可能的反应机理。该方法具有操作简单、反应时间短和环境友好等特点，为四氢噻吩环的构建提供了理论依据。 Cu-MOF/FeOOH composite was prepared and used as catalyst to study the catalytic performance of series cyclization of nitroene and 2,5-dihydroxy-1,4-dithiane in aqueous phase. A series of Tetrahydrothiophene compounds were synthesized in high yield (up to 98%), and the reaction experiments and catalyst recycling were systematically studied. Finally, the possible reaction mechanism was discussed. The method has the characteristics of simple operation, reaction time and environmental friendliness, which provides a theoretical basis for the construction of tetrahydrothiophene ring.