Why the study?
Depression is associated with increased disease activity and decreased treatment response in rheumatoid arthritis, making it a potential intervention target to improve quality of life.
Does nursing intervention reduce depression in patients with rheumatoid arthritis?
RCT (n=100)
Single-blind
Computer-generated sequence of random numbers
No
Does nursing intervention reduce depression in patients with rheumatoid arthritis?
This study protocol aims to evaluate the effectiveness of nursing interventions in reducing depression among patients with rheumatoid arthritis.
Depression intervention in RA may enhance quality of life; extends evidence for targeting psychiatric comorbidity in chronic inflammatory disease.
BACKGROUND: Rheumatoid arthritis (RA) is a kind of chronic disease of inflammatory joint, which can lead to the damage and disability of bone and cartilage. Psychiatric comorbidity is related to the adverse results of RA. Symptoms of depression is associated with the increased disease activity and decreased response to the treatments. Therefore, the depression may be an effective intervention target to improve the life quality and subjective health of the patients with RA. The objective of this experiment is to evaluate the effectiveness of nursing intervention for reducing depression for patients with RA. METHOD: It is a single-center randomized controlled study to be conducted from January 2021 to December 2021. It was admitted via the Ethics Committee of Tianjin Medical University (202018384). One hundred patients are included in the study. The inclusion criteria contains:The exclusion criteria contains:All the patients participating in this study are randomly divided into control group and study group, with 50 patients in each group. The primary result is the severity of depression in the patients with RA, based on the generally utilized questionnaires (Hospital Anxiety and Depression Scale). The secondary outcome is the patients life quality, which is evaluated with the short form 36 questionnaire. The analysis of all the data are conducted with the software of IBM SPSS Statistics for Windows, version 20. RESULTS: Table will show the clinical outcomes after various interventions. CONCLUSION: This paper instructs the nurses to develop protocol based on evidence to improve the clinical efficacy for the RA patients. TRIAL REGISTRATION NUMBER: researchregistry6114.
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Liu et al. (2020) conducted an RCT in Rheumatoid arthritis (n=100). Nursing intervention (depression management training) vs. Routine nursing care was evaluated on Severity of depression (Hospital Anxiety and Depression Scale). A nursing intervention protocol was designed to evaluate its effectiveness in reducing depression severity among patients with rheumatoid arthritis, with results pending trial completion.
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