Answers are grounded in this paper and cite their sources.
We analyzed 3,475 human immunodeficiency virus sequences and 241 therapeutic histories. The L74I mutation was carried by 7% of viruses. L74I was strongly associated with T215F, K70R, and V75M/S/T/A mutations and increased with the number of thymidine analog mutations. It seemed to be linked to the use of abacavir or efavirenz.
No takes yet. Share an insight, caveat, or question.
Wirden et al. (2006) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: