Population
146 nasopharyngeal/oropharyngeal swabs of COVID-19 cases
Key result
Sequencing of 146 COVID-19 swabs in India revealed that 15 (10.3%) contained a combination of L452R and E484Q mutations in the spike protein receptor-binding domain.
Authors
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Detection of L452R+E484Q in Indian isolates warrants vigilance; leaves open effects on transmissibility or immune evasion.
The B.1.617.1 variant with combined L452R and E484Q mutations was identified in COVID-19 cases in India, raising concerns about potential impacts on vaccine efficacy.
Yadav et al. (2021) conducted a letter in COVID-19 (n=146). SARS-CoV-2 variant sequencing was evaluated on Presence of combined L452R and E484Q mutations. Sequencing of 146 COVID-19 swabs in India revealed that 15 (10.3%) contained a combination of L452R and E484Q mutations in the spike protein receptor-binding domain.