Why the study?
Are adhesive platelet estimations clinically useful for detecting thrombosis after surgery or during long-term anticoagulant therapy?
Are adhesive platelet estimations clinically useful for detecting thrombosis after surgery or during long-term anticoagulant therapy?
Adhesive platelet counts lack clinical utility for detecting thrombosis post-surgery or during long-term anticoagulation.
Adhesive platelet counts should not inform thrombosis detection after surgery or during anticoagulation; leaves open development of alternative biomarkers.
It has been found that adhesive platelet counts are not of clinical use either after surgical operation or during long-term anticoagulant therapy in the detection of thrombosis. Calculation of the theoretical risk of development of platelet thrombi related to the platelet count suggests a possible reason for this absence of clinical significance. The evidence that platelet adhesiveness alters because of uncontrollable platelet variables and is controlled at least in part by plasma factors is discussed. The possibility of measuring the plasma factors is considered briefly.
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R. D. Eastham (1970) studied this question.
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