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January 12, 1970Acta Medica Scandinavica

Platelet Adhesiveness in Coronary Heart Disease

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Key result

Platelet adhesiveness assessment using platelet-rich plasma with ADP failed to show any difference between prospective and post-infarction groups of men of the same age.

Why the study?

Does measuring platelet adhesiveness using platelet-rich plasma with ADP detect coronary-prone patients?

Population

Men, including a prospective group and a post-infarction group of the same age

Comparison

Measurement of platelet adhesiveness using… vs Prospective group compared to post-infarction…

Design

Cohort

Authors

HSHelge StormorkenOslo University Hospital

Discussion

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Implication

Does not support ADP platelet adhesiveness testing for coronary risk stratification; leaves open whether refined assays may identify at-risk patients.

Study Design

Type

Observational

Structured PICO

Does measuring platelet adhesiveness using platelet-rich plasma with ADP detect coronary-prone patients?

P
Population
Men in prospective and post-infarction groups assessed for platelet adhesiveness.
E
Exposure
Measurement of platelet adhesiveness using platelet-rich plasma with ADP
C
Comparator
Prospective group compared to post-infarction group
O
Outcome
Difference in platelet adhesiveness between groupssurrogate

Assessing platelet adhesiveness using platelet-rich plasma with ADP is not a useful method for identifying patients at risk for coronary heart disease.

Limitations

  • Large day-to-day variations in the method
  • Large day-to-day variations

Cite This Study

Helge Stormorken (1970) conducted an observational in Coronary heart disease. Platelet adhesiveness assessment using platelet-rich plasma with ADP vs. Prospective vs post-infarction group was evaluated on Difference in platelet adhesiveness. Platelet adhesiveness assessment using platelet-rich plasma with ADP failed to show any difference between prospective and post-infarction groups of men of the same age.

synapsesocial.com/papers/6aa2d1bbfd3136035ea7392ahttps://doi.org/10.1111/j.0954-6820.1970.tb08048.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Observations on the Measurement of Platelet Adhesiveness with the Glassbead Column Technique1968 · 5 citations
  2. 2Seasonal Fluctuation in Adhesive Platelets during Long‐Term Anticoagulant Therapy*1966 · 12 citations
  3. 3Thrombocytoasthenia and Thrombocytopathia—Old Names and New Diseases1956 · 80 citations
  4. 4Quantitative assessment of fibrosis and steatosis in liver biopsies from patients with chronic hepatitis C2001 · 109 citations