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November 1, 1967Journal of Clinical PathologyOpen Access

Platelet adhesiveness in diabetes mellitus

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Why the study?

Is platelet adhesiveness increased in patients with diabetes mellitus compared to control subjects?

Population

34 diabetic patients and 50 control subjects

Comparison

Diabetes mellitus (observational exposure) vs Control subjects

Design

Case-control

Authors

SSSidney ShawDalhousie UniversityGPG. D. PegrumCharing Cross HospitalSWS. WolffCharing Cross Hospital

Discussion

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Implication

May mediate excess vascular risk in diabetes; hypothesis-generating and should not yet change practice.

Structured PICO

Is platelet adhesiveness increased in patients with diabetes mellitus compared to control subjects?

P
Population
34 diabetic patients and 50 control subjects
I
Intervention
Diabetes mellitus (observational exposure)
C
Comparator
Control subjects
O
Outcome
Platelet adhesiveness (assessed using adenosine diphosphate and adherence to glass microspherules)surrogate

This study demonstrates that platelet adhesiveness is significantly increased in patients with diabetes mellitus, providing a potential mechanism for their increased vascular risk.

Cite This Study

Shaw et al. (1967) studied this question.

synapsesocial.com/papers/6a9918acee2e02d2bfe10bb8https://doi.org/10.1136/jcp.20.6.845
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ADENOSINEDIPHOSPHATE INDUCED PLATELET ADHESIVENESS IN DIABETES MELLITUS WITH COMPLICATIONS1971 · 43 citations
  2. 2ADENOSINE‐DIPHOSPHATE‐INDUCED PLATELET ADHESIVENESS IN PATIENTS WITH ISCHAEMIC HEART DISEASE1970 · 9 citations
  3. 3Platelets and Diabetes Mellitus1977 · 163 citations
  4. 4Increased Platelet Aggregation in Early Diabetus Mellitus1975 · 308 citations
  5. 5Blood Platelet Behaviour in Patients with a Type I Diabetes Mellitus2009 · 11 citations