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December 15, 1977New England Journal of Medicine

Platelets and Diabetes Mellitus

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Population

Patients with diabetes mellitus

Design

Review

Authors

JMJ. F. MustardGeneral / Preventive / LipidsMPMarian A. PackhamUniversity of Toronto

Discussion

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Implication

Platelets from diabetic patients exhibit heightened sensitivity to aggregation, which may contribute to their increased susceptibility to atherosclerotic complications.

Structured PICO

P
Population
Patients with diabetes mellitus
O
Outcome
Platelet adhesiveness and aggregationsurrogate

Platelets from diabetic patients exhibit heightened sensitivity to aggregation, which may contribute to their increased susceptibility to atherosclerotic complications.

Cite This Study

Mustard et al. (1977) studied this question.

synapsesocial.com/papers/6a0accc99b4eb2f7ce2e19b6https://doi.org/10.1056/nejm197712152972408
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1On the Measurement of Spontaneous Platelet Aggregation. The Platelet Aggregation Test III.1976 · 75 citations
  2. 2Increased Synthesis of Prostaglandin-E-like Material by Platelets from Patients with Diabetes Mellitus1977 · 198 citations
  3. 3Heterogeneity of human platelets1969 · 322 citations
  4. 4Platelet hypersensitivity induced by cholesterol incorporation.1975 · 462 citations
  5. 5The effect of platelet age on platelet adherence to collagen1968 · 140 citations