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January 12, 1970Acta Medica Scandinavica

Adenosine‐diphosphate‐induced Platelet Adhesiveness in Patients With Ischaemic Heart Disease

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Why the study?

Is adenosine-diphosphate-induced platelet adhesiveness increased in patients with previous myocardial infarction or insulin-treated diabetes compared to healthy controls?

Population

120 individuals: 50 patients with previous myocardial infarction, 50 matched controls, and 20…

Comparison

Previous myocardial infarction or… vs Matched healthy controls

Design

Case-control

Authors

ASA. SjögrenLillebaelt HospitalLBL. E. BöttigerUppsala UniversityGBGunnar BiörckUppsala University Hospital

Discussion

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Implication

Does not support adhesiveness testing to identify prior MI; leaves open its association with thrombotic risk in insulin-treated diabetes.

Structured PICO

Is adenosine-diphosphate-induced platelet adhesiveness increased in patients with previous myocardial infarction or insulin-treated diabetes compared to healthy controls?

P
Population
120 individuals: 50 patients with previous myocardial infarction, 50 matched controls, and 20 insulin-treated diabetics.
I
Intervention
Previous myocardial infarction (ischaemic heart disease) or insulin-treated diabetes
C
Comparator
Matched healthy controls
O
Outcome
Adenosine-diphosphate-induced platelet adhesiveness to glass beadssurrogate

Adenosine-diphosphate-induced platelet adhesiveness is not significantly increased in patients with previous myocardial infarction compared to matched controls, but is elevated in insulin-treated diabetics.

Cite This Study

Sjögren et al. (1970) studied this question.

synapsesocial.com/papers/6a901371ed78fcc1e60d2cbchttps://doi.org/10.1111/j.0954-6820.1970.tb02912.x
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet adhesiveness in diabetes mellitus1967 · 58 citations
  2. 2Adhesiveness of Blood Platelets in Thromboembolism and Hemorrhagic Disorders: II. Diagnostic and Prognostic Significance of Platelet Adhesiveness1949 · 49 citations